WHAT IS A PROSCAN TABLET HOW TO
WHAT IS A PROSCAN TABLET FULL

These undesirable effects are reversible when treatment is discontinued or when the dose is reduced. Micronodular changes in the corpus mammae may occur. Monotherapy: The most common undesirable effects observed during clinical trials using Proscan are gynecomastia and/or chest pain, sometimes accompanied by galactorrhea. What are the possible side effects of Proscan? Therefore, close monitoring of prothrombin time is recommended and adjustment of the anticoagulant dose may be necessary when Proscan (Proscan) Capsules are administered concomitantly with warfarin. Increases in prothrombin time have been noted in patients receiving long- term warfarin therapy after Proscan was initiated. When treating single stage D2 metastatic carcinoma, Proscan should be initiated with the LHRH agonist and continued until progression. When treating B2-C prostatic carcinoma, Proscan and LHRH agonists should be started 8 weeks prior to initiating radiation therapy and continued during radiation therapy. Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).ĭoses > 750 mg/day are not recommended. Baseline liver function tests and periodic monitoring during therapy is recommended. Rare, sometimes fatal, cases of cholestatic jaundice, massive hepatic necrosis, and hepatic encephalopathy have been reported. However, FDA approved package labeling states that Proscan has no indication for women, and should not be used in this population, particularly for nonserious or non-life threatening conditions.Ĭonsider dosage reduction in patients with liver disease based on desired clinical response and patient tolerance.Įlevations in liver function tests have been reported. Always consult your doctor or pharmacist.įor use in locally confined stage B2-C and stage D2 metastatic carcinoma of the prostate: 250 mg orally every 8 hours.ĭata has been reported in which 250 mg of Proscan 2 to 3 times daily in combination with oral contraceptives has been used in the treatment of female patients with hirsutism. The information at is not a substitute for medical advice. Proscan dosageĪpplies to the following strength(s): 125 mg Proscan also contains the following ingredients: Sodium lauryl sulfate, microcrystalline cellulose, maize starch, lactose monohydrate, colloidal, anhydrous sillica, magnesium stearate. However, older antiandrogen agents may be offered in patients with low prostate cancer disease burden or limited therapy options (ASCO ). Guideline recommendations: The American Society of Clinical Oncology and Cancer Care Ontario clinical practice guideline for systemic therapy in men with metastatic castration-resistant prostate cancer suggests that data regarding the clinical benefit of older antiandrogens (including Proscan) are limited, and that older antiandrogen agents may be less efficacious compared to contemporary antiandrogen agents. Prostate cancer (metastatic): Management of locally confined Stage B metastatic prostate cancer, initiate Proscan with the LHRH agonist and continue until disease progression.

WHAT IS A PROSCAN TABLET HOW TO

Do not take 2 doses at once.Īsk your health care provider any questions you may have about how to use Proscan. If you miss a dose of Proscan, skip the missed dose and go back to your regular dosing schedule.Read it carefully and reread it each time you get Proscan refilled. Proscan comes with an additional patient leaflet.

WHAT IS A PROSCAN TABLET FULL

Take Proscan with a full glass of water (8 oz/240 mL).

If stomach upset occurs, take with food to reduce stomach irritation.

Proscan may be taken with or without food.

Check the label on the medicine for exact dosing instructions. To achieve benefit from treatment, Proscan capsules should be initiated with the LHRH agonist and continued until progression. Treatment with Proscan capsules and the goserelin acetate implant should start 8 weeks prior to initiating radiation therapy and continue during radiation therapy. Proscan capsules are indicated for use in combination with LHRH agonists for the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate.

What is a proscan tablet